Your question is not exactly clear, but if you are asking how to play a H17 game, there really isn't that much different to it than a S17 game except that you need to know that you start off with a little more of a disadvantage and a few plays are slightly different. As far as you answer about reactive and proactive measures, you will have to clarify that becuase I am not familiar with your choice of words. Penetration is a good way to increase your edge at H17, but if thats not what you're looking for then you need to explain to me what a proactive process is....sorry I failed English, good thing I got an A in statistics.
.. the ones I can recall that change, with Hilo indeces:
Soft 18 v A (always hit)
Hard 16 v A (stand on +3, not +9)
Hard 15 v A (stand on +6, dunno what it is for S17)
Double 11 v A, double A7 v 2 (0 instead of +1)
Double A8 v 6 (-1 instead of +1)
Late Surrender 15 v A (-3)
Late Surrender 17 v A (+1 OR LESS)
Split 99 v A (+1 instead of +3)
That's only worth about -0.19%. Don't be penny wise & dollar foolish, and take a look at the difference in 80% pen vs 60%. Depending on the game (you didn't give the specifics of the game available to you), the 80% pen could have an EV around 1.5 to 2 times higher than the same game with 60% pen.
Always remember the three most important game rules/conditions with respect towards EV:
1. Good pen
2. Good pen
3. Good pen
The next on my list would be hands/hr. Bet size/spreads tolerated would also be high priority. Rules such as H17, RSA, DAS, etc. are certainly worth consideration and you should always adjust to the correct play for the rules of a particuliar game, but these more common rules variations are generally far down the list in importance to EV. An exception might be 2-1 or even money BJ payoffs, which are worth plus & minus 2.3% respectively compared to the normal 3-2 payoff, and maybe ES, all of which I don't consider "common variations" anyway.