TheWizardofOdds.com gives you the strategy. You'll need to run a sim for the indices. It is beatable, at least the game I looked at, but you'll need an aggressive spread & if you want to make a decent hourly rate probably a hefty bankroll.
If you're playing BJ too you may find it confusing jumping between
BTW, it's listed under it's more common name of Spanish 21.
that Pontoon and Spanish 21 are the same game. There are separate pages for each game on wizardofodds.com. Furthermore, rule 1. for Pontoon on http://www.wizardofodds.com/games/pontoon.html states, "The game is played with eight 52-card decks." This tells us that the tens are NOT removed from the decks as is done for Spanish 21.